Buffalo’s perfect start ends at 4-1 after a 23-20 loss to New England as Josh Allen and the Bills offense struggled to sustain big plays. Allen labeled the night “piss poor offense” after a late field goal gave the Patriots the win. Buffalo moved the ball but stalled in critical moments, while the defense kept New England’s attack in check. Dalton Kincaid led Bills receivers with 108 yards on six catches, and James Cook churned for 49 on 15 carries. Buffalo’s next test comes on the road against Atlanta.

Milano's return shores up Buffalo's defense for the Week 5 primetime clash with New England, but interior depth is thin with Ed Oliver and TJ Sanders out and Dorian Williams inactive. Landon Jackson will debut, while Zion Logue and Phidarian Mathis join the DT rotation. Curtis Samuel earns a jersey as Elijah Moore remains inactive, and Samuel/Khalil Shakir provide return opportunities with Johnson handling kicks. Jimmy Ciarlo is active after a late roster move.

Fantasy angles center on how Logue/Mathis anchor the interior and whether Jackson can spark the edge rush, plus how Samuel, Johnson, and Shakir contribute in return duties and short-yardage packages against New England.

Buffalo hosts New England in a primetime SNF clash that sparks heavy Bills-centric DFS action. Josh Allen and James Cook sit at the core of most lineups, with Stefon Diggs and Khalil Shakir offering high-ceiling, mid-range complements. Drake Maye and Keon Coleman are presented as contrarian pivots, while Dalton Kincaid and Rhamondre Stevenson provide viable value options in a game expected to pace highly. Expert Mike McClure’s model underpins the top stacks and suggests selective diversifications for tournaments.

SNF Week 5 centers on a Patriots-Bills clash, with Drake Maye lining up as a solid mid-range QB1 and Rhamondre Stevenson anchoring the Patriots’ backfield behind him. TreVeyon Henderson sits behind Stevenson but could pop for a score, while Stefon Diggs, Dalton Kincaid, and Khalil Shakir anchor Buffalo’s aerial attack. Hunter Henry toning up as a reliable tight end adds a safe floor.

The free Who Should I Start tool shines for Week 5, letting you compare up to four players and derive a precise start/sit verdict. The week’s hottest searches show a mix of upside and risk, underscoring the nuance of SNF decisions in fantasy football.